Artist: EC8OR: mp3 download Genre(s): Other EC8OR's discography: All of Us Can Be Rich Year: 1997 Tracks: 14 Cologne-bred, Berlin-based Patric C. (aka EC8OR) is one of the most fat of the younger generation of "digital hardcore" artists combination hardcore breakbeat and gabber techno with elements of tinder rock, speeding alloy, and observational randomness. Recording and playing under a half xII pseudonyms (including Eradicator, E-De Cologne, Irish Coffee, and Test-Tube Boy), Patric C.'s EC8OR work is ordinarily in quislingism with adolescent strong-armer singer Gina D'Orio (in one case of the Lemonbabies and Throw That Beat), and through their association with Alec Empire's Digital Hardcore Recordings pronounce, they've managed to turn ane the near popular and long-familiar artists on the German hard-core scene. Using only an Amiga 500 (a garish, jolly disused screen background computer with built-in sequencing and sampling capabilities), Patric began recording in 1991 after quitting school to immerse himself in the emergent rant scene. Releasing tracks literally out of his travel bag, Patric's low gear twelves of comparatively straightforward techno appeared through Cologne's noted Structure label mathematical group (which included imprint's such as DJ Ungle Fever, Mono Tone, and Profan along with artists such as Mike Ink, Air Liquide, and Biochip C.). Patric's sexual making love of rap music, goon, and death alloy didn't picture through and through in the music until he began making breakbeat gabber, nevertheless -- a style which linked him with hardcore sulfurous and techno labels such as Shockwave, Fischkopf (through which he released his debut LP, Agitprop), and, finally, DHR. The group's association with the latter judge has in all probability been the most all important; in addition to a number of singles and the self-titled EC8OR full-length (released in late 1995), DHR's distribution deal with American mark Grand Royal translated into a far larger interview for their music, with Earth Beaters following in 1998. Two days later EC8OR released the full-length The One and Only High and Low. |
Monday, 25 August 2008
Mp3 music: EC8OR
Friday, 15 August 2008
Download Chayanne
Artist: Chayanne: mp3 download Genre(s): Latin Pop: Latin Pop Rock Discography: Mi Tiempo Year: 2007 Tracks: 11 Desde Siempre Year: 2005 Tracks: 12 Cautivo Year: 2005 Tracks: 10 Sincero Year: 2003 Tracks: 12 Grandes Exitos Year: 2002 Tracks: 17 Simplemente Year: 2000 Tracks: 13 Sangre Latina Year: 1999 Tracks: 10 Atado a Tu Amor Year: 1998 Tracks: 13 Volver a Nacer Year: 1996 Tracks: 11 Influencias Year: 1994 Tracks: 10 Provocame Year: 1992 Tracks: 11 Tiempo de Vals Year: 1990 Tracks: 9 Chayanne Year: 1989 Tracks: 10 Chayanne es mi nombre Year: 1984 Tracks: 10 Beginning in the late '80s, Chayanne, one of Latin pop's premier heartthrobs, sustained a plentiful hitmaking career as a balladeer and fifty-fifty establish time to act on an playacting vocation on the side. Born Elmer Figueroa-Arce on June 28, 1968, in San Lorenzo, Puerto Rico, the isaac Bashevis Singer began his life history in 1979 at years 11, when he coupled the Puerto Rican boy band Los Chicos. Designed to match Menudo, which was the preeminent male child band of the earned run average, Los Chicos failed to reach forbidden a comparably hectic horizontal surface of popularity, though they were commercially successful enough to warrant a made-for-TV celluloid, Conexión Caribe (1984), as good as a weekly TV picture on Puerto Rico's WAPA-TV. Los Chicos released five-spot albums -- Para Amar (1980), Puerto Rico (1980), Viva el Amor (1982), Bailando al Ritmo de la Lluvia (1983), and Conexión Caribe (1984) -- in front conclusion their run in 1984. Almost immediately, Chayanne embarked on a solo life history, debuting with Chayanne Es Mi Nombre (1984) for RCA Records. Sangre Latina (1986) followed, simply it wasn't until Chayanne touched to Sony for a sequent match of eponymic albums in 1988 and 1989 that his solo career began to carry fruit. His 1989 record album in peculiar was a murder, earning him a Grammy nomination for Best Latin Pop Performance; major hits included "Fiesta en America," "Violeta," "Te Deseo," and "Para Tenerte Otra Vez," which were re-recorded in Portuguese, as was the remainder of the record record album itself, for a successful Brazilian crosswalk. Also in 1989, Chayanne notably sign a contract with Pepsi to record the showtime Spanish-language commercial airy in the United States on a major TV electronic network without subtitles or dubbing, debuted during the Grammy Awards that year. Henceforth Chayanne would delight regular success, releasing hit albums roughly every two days: Tiempo de Vals (1990), Provocame (1992), Influencias (1994), Volver a Nacer (1996), Atado a Tu Amor (1998), Simplemente (2000), Sincero (2003), Cautivo (2005). Each sold better than its predecessor, for the intimately voice. Greatest-hits compilations such as Grandes Exitos (2002) and Desde Siempre (2005) would overly be issued from clipping to time. Chayanne's hits are as well numerous to list, though it is worth pointing kO'd his particularly energetic association with songster Estéfano. In addition to vocalizing, Chayanne is a gifted dancer and role participant, with a growing identification number of telenovela and cinema roles to his course credit entry. |
Thursday, 7 August 2008
Avastin Cancer Drug Linked To Anemia In Combo Trials Doctors Warned
�On Monday, the US Food and Drug Administration (FDA) posted on its website, a copy of a letter from Genentech Inc, the makers of cancer
drug Avastin, to healthcare providers that warns them around a eccentric anemia seen in clinical trial patients treated with Avastin in combination with Pfizer
Inc's Sutent (sunitinib malate).
Microangiopathic hemolytic anemia, or MAHA, is a type of anemia (shortage of red stemma cells) caused by a build up of platelets and other organic
obstructions on the inner walls of very small blood vessels. These shred healthy red blood cells as they pass through, finally leading to a a whole
body shortage of them.
Avastin, which works by cutting off the blood supply that feeds tumors, is sanctioned for the treatment of colon, lung and boob cancer, and according
to Reuters, is widely considered to be Genentech's most important product, with second quarter results in the US anticipated to be around 640 million
dollars. The dose is currently undergoing a number of trials to test its safety and efficacy in combination with a range of other drugs.
The varsity letter states that a combination of Avastin and Sutent, a do drugs that is widely used for treating advanced kidney cancer, is neither recommended nor
approved and that a Phase 1 dose-escalation study looking at the safety and efficacy of the combination in 25 patients was stopped early because 5
of the 12 patients on the highest Sutent dose had symptoms consistent with MAHA.
The patients were in three groups, each taking a frozen dose of Avastin at 10 mg/kg/IV every 2 weeks, with the number one on 25, the sec on 37.5 and the
third on 50 mg day-after-day oral dot of Sutent in a 4 week on and 2 week off schedule.
Two of the five MAHA-consistent cases were classed as severe, with evidence of:
"Thrombocytopenia, anemia, reticulocytosis, reductions in serum haptoglobin, schistocytes on peripheral stain, modest increases in serum
creatinine levels, and stern hypertension, reversible posterior leukoencephalopathy syndrome (RPLS), and proteinuria."
However, in both cases, these symptoms were reversed inside three weeks of stopping the combination drugs and without whatsoever additional treatment.
According to Reuters, Kimberly O'Campo, speaking for Genentech, aforesaid that other studies on Avastin in combination with lower doses of Sutent are
still ongoing, only two other mid-stage studies of the two drugs with chemotherapy, involving patients with white meat and lung cancer, were stopped
because of fatigue, gastrointestinal complications and myelosuppression, a condition that reduces blood cell and thrombocyte production.
The alphabetic character asks wellness professionals to report cases of MAHA, or whatsoever other serious adverse event that they suspect arose from or in association with
function of Avastin.
Click here to see the Genentech alphabetic character to
healthcare providers (PDF).
Sources: FDA, Reuters.
Written by: Catharine Paddock, PhD
View drug information on Avastin; Sutent.
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today
More info
drug Avastin, to healthcare providers that warns them around a eccentric anemia seen in clinical trial patients treated with Avastin in combination with Pfizer
Inc's Sutent (sunitinib malate).
Microangiopathic hemolytic anemia, or MAHA, is a type of anemia (shortage of red stemma cells) caused by a build up of platelets and other organic
obstructions on the inner walls of very small blood vessels. These shred healthy red blood cells as they pass through, finally leading to a a whole
body shortage of them.
Avastin, which works by cutting off the blood supply that feeds tumors, is sanctioned for the treatment of colon, lung and boob cancer, and according
to Reuters, is widely considered to be Genentech's most important product, with second quarter results in the US anticipated to be around 640 million
dollars. The dose is currently undergoing a number of trials to test its safety and efficacy in combination with a range of other drugs.
The varsity letter states that a combination of Avastin and Sutent, a do drugs that is widely used for treating advanced kidney cancer, is neither recommended nor
approved and that a Phase 1 dose-escalation study looking at the safety and efficacy of the combination in 25 patients was stopped early because 5
of the 12 patients on the highest Sutent dose had symptoms consistent with MAHA.
The patients were in three groups, each taking a frozen dose of Avastin at 10 mg/kg/IV every 2 weeks, with the number one on 25, the sec on 37.5 and the
third on 50 mg day-after-day oral dot of Sutent in a 4 week on and 2 week off schedule.
Two of the five MAHA-consistent cases were classed as severe, with evidence of:
"Thrombocytopenia, anemia, reticulocytosis, reductions in serum haptoglobin, schistocytes on peripheral stain, modest increases in serum
creatinine levels, and stern hypertension, reversible posterior leukoencephalopathy syndrome (RPLS), and proteinuria."
However, in both cases, these symptoms were reversed inside three weeks of stopping the combination drugs and without whatsoever additional treatment.
According to Reuters, Kimberly O'Campo, speaking for Genentech, aforesaid that other studies on Avastin in combination with lower doses of Sutent are
still ongoing, only two other mid-stage studies of the two drugs with chemotherapy, involving patients with white meat and lung cancer, were stopped
because of fatigue, gastrointestinal complications and myelosuppression, a condition that reduces blood cell and thrombocyte production.
The alphabetic character asks wellness professionals to report cases of MAHA, or whatsoever other serious adverse event that they suspect arose from or in association with
function of Avastin.
Click here to see the Genentech alphabetic character to
healthcare providers (PDF).
Sources: FDA, Reuters.
Written by: Catharine Paddock, PhD
View drug information on Avastin; Sutent.
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today
More info
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